While DDR3-1600 operating under tight timings will undoubtedly give you the best performance, and DDR3 below 1066 should not be used for the sake of performance, the best compromise clearly is DDR3-1333 at reasonable timings. In most benchmarks, the difference between 1600 and 1333 speeds is negligible, but 1333 would still give you a larger benefit than the tiny gap between 1333 and 1600. In addition, DDR3-1333 is about to become the performance mainstream level, meaning acceptable prices for low-latency memory kits.

DDR3 1333 is getting cheaper as you can see here.

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